Optical Sorting 细胞分选系统 by Yuanyuan Liu is a highly esteemed winner of the very prestigious 2025 A' Design Award 金奖 in 科学仪器与研究设备设计 Competition Category.

金科学仪器· 2025

Optical Sorting 细胞分选系统

by Yuanyuan Liu

A' Design Award 金奖 Winner in 科学仪器 Category

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Verified Award Winner
Verify Award Status for #166755

View at A' Design Award Press Release Award Badge

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The Design

About Optical Sorting 细胞分选系统

光学分选是一套面向生物医学研究开发的光学细胞分选系统。细胞被加载至微流控芯片中,并通过光诱导介电泳进行导引,从而在不损伤样本的前提下完成分选。成像系统对细胞进行记录,软件则实时分析图像,以识别并分类每一个细胞。分选后的细胞随后被收集,用于培养及进一步研究。该系统可同时处理数万个单细胞,因而阳性浆细胞筛选可在一天内完成。仪器尺寸为60 × 80 × 170厘米。

The Recognition

About the A' Design Award 金奖

Optical Sorting 细胞分选系统是 A' Design Award 金奖得主，这是授予一流、绝妙而杰出设计的极为崇高的认可。金奖得主是极具创新、极富远见且璀璨夺目的创作，反映出其设计师的天才、智慧与才干。预计Optical Sorting 细胞分选系统将成为一项备受赞誉、引领潮流、气势恢宏的发明，带来前所未有的价值。这件赢得 A' Design Award 金奖的设计是一个壮观而受人敬重的项目，极大地造福并拓展艺术、科学、设计和技术的边界。Optical Sorting 细胞分选系统激起强烈的渴望，唤起激情，鼓励创造力，令我们着迷。

Behind the Design

Press Kit

Credits, team members and technical details provided by the designer.

Unique Properties: Efficiently screening and analyzing antibody discovery is crucial for reducing time and costs in antibody drug development. Traditional hybridoma technology faces challenges like long cycles, limited diversity, and inadequate functional analysis, hindering progress. The AI nanobiochip technology in the Light Workbench can rapidly separate, analyze, culture, and export tens of thousands of single cells simultaneously, completing positive plasma cell screening in one day.
Dimensions & Packaging: 60cm*80cm*170cm
Tags: cell, instrument， Biological
Production Technology: Such products may utilize a variety of production technologies, including optical-induced dielectrophoresis, microfluidics, micro-nano fabrication, laser technology, imaging and detection, as well as automation and control. These technologies work in concert to achieve precise manipulation, efficient sorting, rapid analysis, and automated processing of cells, thereby providing powerful tools for biomedical research.
Research: In our research, we looked into a particular topic to gain more insights. We conducted experiments or studies, using various tools like scientific instruments or software, depending on what we were focusing on. If it involved people, we had participants; if it was about animals or cells, those were our subjects. Through our methods, we observed, collected data, and tested different conditions. The results revealed interesting findings, such as a new relationship or a significant change. These findings gave us new understandings and could point the way for future research.
Inspiration: The Optical Cell Sorting System is a breakthrough in cell sorting for biomedical research. It replaces time-consuming, sample-damaging manual sorting with optoelectronic dielectrophoresis, which precisely controls cells for efficient, undamaged sorting. This technology boosts accuracy and speed, providing a reliable, streamlined cell sorting and culture process. The Light Operator enhances lab efficiency, enabling scientists to advance cell research.
Project Duration: The project started in December 2020 in Beijing and finished in August 2023 in Beijing.
Operation Flow: First, the cells or other biological samples to be sorted are prepared and loaded into the microfluidic chip of the system. Then, the optical-induced dielectrophoresis technology is used to manipulate and sort the cells based on their properties. During this process, the imaging system captures the images of the cells, and the software analyzes the images in real-time to identify and classify the cells. Finally, the sorted cells are collected, and the results are output and processed for subsequent research.
Team Members: Yuanyuan Liu
Hu Yin
Zipeng Zhang
Haocheng Han
Changgen Li