Optical Sorting 細胞分選系統 by Yuanyuan Liu is a highly esteemed winner of the very prestigious 2025 A' Design Award 金獎 in 科學儀器設計 Competition Category.

金科學儀器· 2025

Optical Sorting 細胞分選系統

by Yuanyuan Liu

A' Design Award 金獎 Winner in 科學儀器 Category

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Verified Award Winner
Verify Award Status for #166755

View at A' Design Award Press Release Award Badge

Colors

The Design

About Optical Sorting 細胞分選系統

Optical Sorting係一套為生物醫學研究而開發嘅光學細胞分選系統。細胞會被載入微流控芯片,並透過光誘導介電泳技術引導,喺唔損傷樣本嘅情況下進行分選。成像系統會記錄細胞影像,軟件即時分析呢啲影像,識別同分類每一粒細胞。分選出嚟嘅細胞隨後會被收集,用作培養同進一步研究。系統可以同時處理數以萬計嘅單細胞,所以陽性漿細胞篩選可以喺一日之內完成。儀器尺寸為60乘80乘170厘米。

The Recognition

About the A' Design Award 金獎

Optical Sorting 細胞分選系統是 A' Design Award 金獎得主，這是授予一流、絕妙而傑出設計的極為崇高的認可。金獎得主是極具創新、極富遠見且璀璨奪目的創作，反映出其設計師的天才、智慧與才幹。預計Optical Sorting 細胞分選系統將成為一項備受讚譽、引領潮流、氣勢恢宏的發明，帶來前所未有的價值。這件贏得 A' Design Award 金獎的設計是一個壯觀而受人敬重的項目，極大地造福並拓展藝術、科學、設計和技術的界限。Optical Sorting 細胞分選系統激起強烈的渴望，喚起激情，鼓勵創造力，令我們著迷。

Behind the Design

Press Kit

Credits, team members and technical details provided by the designer.

Unique Properties: Efficiently screening and analyzing antibody discovery is crucial for reducing time and costs in antibody drug development. Traditional hybridoma technology faces challenges like long cycles, limited diversity, and inadequate functional analysis, hindering progress. The AI nanobiochip technology in the Light Workbench can rapidly separate, analyze, culture, and export tens of thousands of single cells simultaneously, completing positive plasma cell screening in one day.
Dimensions & Packaging: 60cm*80cm*170cm
Tags: cell, instrument， Biological
Production Technology: Such products may utilize a variety of production technologies, including optical-induced dielectrophoresis, microfluidics, micro-nano fabrication, laser technology, imaging and detection, as well as automation and control. These technologies work in concert to achieve precise manipulation, efficient sorting, rapid analysis, and automated processing of cells, thereby providing powerful tools for biomedical research.
Research: In our research, we looked into a particular topic to gain more insights. We conducted experiments or studies, using various tools like scientific instruments or software, depending on what we were focusing on. If it involved people, we had participants; if it was about animals or cells, those were our subjects. Through our methods, we observed, collected data, and tested different conditions. The results revealed interesting findings, such as a new relationship or a significant change. These findings gave us new understandings and could point the way for future research.
Inspiration: The Optical Cell Sorting System is a breakthrough in cell sorting for biomedical research. It replaces time-consuming, sample-damaging manual sorting with optoelectronic dielectrophoresis, which precisely controls cells for efficient, undamaged sorting. This technology boosts accuracy and speed, providing a reliable, streamlined cell sorting and culture process. The Light Operator enhances lab efficiency, enabling scientists to advance cell research.
Project Duration: The project started in December 2020 in Beijing and finished in August 2023 in Beijing.
Operation Flow: First, the cells or other biological samples to be sorted are prepared and loaded into the microfluidic chip of the system. Then, the optical-induced dielectrophoresis technology is used to manipulate and sort the cells based on their properties. During this process, the imaging system captures the images of the cells, and the software analyzes the images in real-time to identify and classify the cells. Finally, the sorted cells are collected, and the results are output and processed for subsequent research.
Team Members: Yuanyuan Liu
Hu Yin
Zipeng Zhang
Haocheng Han
Changgen Li